C-C motif chemokine 12 Antibodies

AND Ccl12 ELISA kits, C-C motif chemokine 12 Proteins

Many biological assays use antibodies to detect C-C motif chemokine 12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 12 antibodies...

We validate the specificity of these antibodies to C-C motif chemokine 12 by testing them on tissues known to express Ccl12 positively and negatively. Browse below to find the Ccl12 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ccl12 Infographic by Boster Bio

All Ccl12 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Mouse CCL12/MCP5 ELISA Kit PicoKine®

2 Citations 8 Q&As

Mouse

ELISA

$499
Cat # EK1128
96 wells/kit, with removable strips.

MCP-5 Monocyte Chemotactic Protein-5 Mouse Recombinant Protein (CCL12)

Mouse

$250
Cat # PROTQ62401
5ug, 20ug, 1mg

Mouse CCL12/MCP5 PicoKine® Quick ELISA Kit

Mouse

ELISA

$499
Cat # FEK1128
96 wells/kit, with removable strips.

Ccl12 Overview

Facts about C-C motif chemokine 12.

Ccl12 3D structure. Source: alphafold

C-C motif chemokine 12 (Ccl12)

Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that indicates through CCR2.

Involved in allergic inflammation and the host response to pathogens and might play a pivotal role during early stages of allergic lung inflammation. .

Gene Information

Mouse
Gene Name:	Ccl12
Uniprot:	Q62401
Entrez:	20293

Family

Belongs to:

intercrine beta (chemokine CC) family

Alternative Names

C-C motif chemokine 12; CCL12; chemokine (C-C motif) ligand 12; MCP5; MCP-5; Scya12

Molecular Weight

Mass (kDA):
11.659 kDA

Genomic Context


Mouse

Location:	11 C\|11 49.9 cM
Sequence:	11;

Tissue Specificity

Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.

Diseases

Inflammation
Cholangiocarcinoma
Fibrosis
Inflammatory Response
Granuloma
Nervousness
Pulmonary Fibrosis
Autoimmune Reaction
Malignant Neoplasms
Neoplasms
Asthma
Pain

Autoimmune Diseases
Pneumonia
Virus Diseases
Schistosomiasis Mansoni
Tissue Adhesions
Systemic Infection
Herpesviridae Infections

Pathways

Immune Response
Pathogenesis
Inflammatory Response
Granuloma Formation
Cell Migration
Hypersensitivity
Cell Activation
Phagocytosis
Innate Immune Response
Methylation
Cell Adhesion
Transport
Muscle Cell Proliferation

Chemokine Production
Electron Transport
Aging
Type I Hypersensitivity
Histone Modification
Spermatogenesis
Type I Interferon Production

PTMs

Phosphorylation
Demethylation

Biotinylation
Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ccl12

References

PMID: 8920881 by Jia G.-Q., et al. Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation.

PMID: 8996246 by Sarafi M.N., et al. Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.

2 Publications of Boster C-C motif chemokine 12 Antibodies & ELISA Kits

PubMed ID: 10.1186/s12974-016-0753-x, In vivo inhibition of miR-155 significantly alters post-stroke inflammatory resp...
PubMed ID: 27829437, In vivo inhibition of miR-155 significantly alters post-stroke inflammatory resp...

*More publications can be found for each product on its corresponding product page