ALG3 Antibodies

AND ALG3 ELISA kits, ALG3 Proteins

Many biological assays use antibodies to detect ALG3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALG3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALG3 antibodies...

We validate the specificity of these antibodies to ALG3 by testing them on tissues known to express ALG3 positively and negatively. Browse below to find the ALG3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ALG3 Infographic by Boster Bio

All ALG3 Products

Product

Figures

Specificity

Applications

Price

ALG3 (NM_005787) Human Over-expression Lysate

Human

$628
Cat # LS010195
100 µg

Anti-ALG3 Antibody Picoband™

Human, Mouse

ELISA, Flow Cytometry, WB

$370
Cat # A04688
100 µg/vial

ALG3 Overview

Facts about Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase.

ALG3 3D structure. Source: alphafold

Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3)

Adds the first Dol-P-Man derived mannose within an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol. .

Gene Information

Human
Gene Name:	ALG3
Uniprot:	Q92685
Entrez:	10195

Family

Belongs to:

glycosyltransferase 58 family

Alternative Names

alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 3 homolog (S. cerevisiae; asparagine-linked glycosylation 3 homolog (yeast; asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S.cerevisiae); Asparagine-linked glycosylation protein 3 homolog; carbohydrate deficient glycoprotein syndrome type IV; CDGS4D16Ertd36e; Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; dol-P-Man dependent alpha(1-3)-mannosyltransferase; Dol-P-Man-dependent alpha(1-3)-mannosyltransferase; EC 2.4.1.130;

Molecular Weight

Mass (kDA):
50.126 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (184242301..184258301, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Congenital Disorders
Endometriosis, Site Unspecified
Congenital Disorders Of Glycosylation
Microcephaly
Inborn Errors Of Metabolism
De Novo Mutation
Muscle Hypotonia
Epilepsy
Cancer Patients And Suicide And Depression
Optic Atrophies, Hereditary
Uterine Cervical Neoplasm
Malignant Tumor Of Cervix

Carcinogenesis
Carcinoma
Dandy-walker Syndrome
Fracture
Malignant Neoplasms
Neoplasms
Psychomotor Disorders

Pathways

Glycosylation
Secretion
Methylation
Protein Glycosylation
Localization
N-glycan Processing
Cellular Localization

Rna Localization
Protein Processing

PTMs

Glycosylation
Cleavage

Methylation
Amination

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALG3

References

PMID: 10581255 by Koerner C., et al. Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.

PMID: 15840742 by Sun L., et al. Congenital disorder of glycosylation Id presenting with hyperinsulinemic hypoglycemia and islet cell hyperplasia.