ABCD3 Antibodies

AND ABCD3 ELISA kits, ABCD3 Proteins

Many biological assays use antibodies to detect ABCD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCD3 antibodies...

We validate the specificity of these antibodies to ABCD3 by testing them on tissues known to express ABCD3 positively and negatively. Browse below to find the ABCD3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABCD3 Infographic by Boster Bio

All ABCD3 Products

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Product

Figures

Specificity

Applications

Price

Anti-PMP70/ABCD3 Antibody Picoband®

3 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA2091
100 μg/vial

Anti-PMP70 ABCD3 Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M02370
100 μl

ABCD3 Overview

Facts about ATP-binding cassette sub-family D member 3.

ABCD3 3D structure. Source: alphafold

ATP-binding cassette sub-family D member 3 (ABCD3)

Probable transporter involved in the transportation of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter purpose is a crucial step in bile acid biosynthesis (PubMed:25168382). The nucleotide-binding fold functions as an ATP- binding subunit with ATPase activity (PubMed:11248239).

Gene Information

Human
Gene Name:	ABCD3
Uniprot:	P28288
Entrez:	5825

Family

Belongs to:

ABC transporter superfamily

Alternative Names

70 kDa peroxisomal membrane protein; ABC43; ATP-binding cassette, sub-family D (ALD), member 3; peroxisomal membrane protein 1 (70kD, Zellweger syndrome); Peroxisomal membrane protein-1 (70kD); PMP70ATP-binding cassette sub-family D member 3; PXMP1dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); ZWS2

Molecular Weight

Mass (kDA):
75.476 kDA

Genomic Context


Human

Location:	1p21.3
Sequence:	1; NC_000001.11 (94418086..94518663)

Subcellular Localizations

Peroxisome membrane; Multi-pass membrane protein.

Diseases

Adrenoleukodystrophy
Zellweger Syndrome
Neurodegenerative Disorders
Peroxisomal Disorders
Neoplasms
Malignant Neoplasms
Inflammation
Nervousness
Demyelination
Demyelinating Diseases
Liver Carcinoma
Glioma

Protein Deficiency
Adrenomyeloneuropathy
Transient Ischemic Attack
Hepatoblastoma
Infantile Refsum Disease (disorder)
Infarction

Interacting Proteins

ABCD1
PEX19

Pathways

Transport
Localization
Pathogenesis
Fatty Acid Beta-oxidation
Translation
Membrane Biogenesis
Protein Import
Fatty Acid Oxidation
Rna Interference
Protein Targeting
Fatty Acid Elongation
Brain Development
Proteolysis

Immune Response
Hepatocyte Proliferation
Spermatogenesis
Inflammatory Response
Reverse Transcription
Fatty Acid Transport
Cell Differentiation

PTMs

Oxidation
Phosphorylation

Cleavage
Reduction

Farnesylation

Research Areas

ABC Transporters
Cellular Markers
Lipid and Metabolism
Neuroscience
Peroxisome Markers

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCD3

References

PMID: 1301993 by Gaertner J., et al. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome.

PMID: 1536884 by Kamijo K., et al. Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters.