AIMP1 Antibodies

AND AIMP1 ELISA kits, AIMP1 Proteins

Many biological assays use antibodies to detect AIMP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AIMP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AIMP1 antibodies...

We validate the specificity of these antibodies to AIMP1 by testing them on tissues known to express AIMP1 positively and negatively. Browse below to find the AIMP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AIMP1 Infographic by Boster Bio

All AIMP1 Products

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Applications

Price

Anti-AIMP1 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A03109
0.1 mg

Human EMAP-II Recombinant Protein

SDS-PAGE

$350
Cat # PROTQ12904
Starting from 10ug

AIMP1 Overview

Facts about Aminoacyl tRNA synthase complex-interacting multifunctional protein 1.

AIMP1 3D structure. Source: alphafold

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1)

Non-catalytic part of the multisynthase complex. Stimulates the catalytic action of cytoplasmic arginyl-tRNA synthase (PubMed:10358004).

Binds tRNA. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (By similarity).

Gene Information

Human
Gene Name:	AIMP1
Uniprot:	Q12904
Entrez:	9255

Family

Belongs to:

No superfamily

Alternative Names

AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; EMAP-2; EMAPII; EMAP-II; EMAPIImember 1 (endothelialmonocyte-activating); endothelial-monocyte activating polypeptide II; Multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; SCYE1

Molecular Weight

Mass (kDA):
34.353 kDA

Genomic Context


Human

Location:	4q24
Sequence:	4; NC_000004.12 (106315610..106349456)

Subcellular Localizations

Nucleus. Cytoplasm, cytosol. Secreted. Endoplasmic reticulum. Golgi apparatus. Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Secreted in response to hypoxia (PubMed:10850427). Also secreted in response to both apoptotic and necrotic cell death.

Diseases

Malignant Neoplasms
Neoplasms
Tumor Angiogenesis
Inflammation
Stomach Neoplasms
Pelizaeus-merzbacher Disease
Neurodegenerative Disorders
Malignant Neoplasm Of Stomach
Asthma
Bronchial Hyperreactivity
Leukodystrophy

Adenoma
Uterine Cervical Neoplasm
Leukoencephalopathies
Malignant Neoplasm Of Lung
Fibrosarcoma
Innate Immune Response

Interacting Proteins

AIMP2
OPTN
TSNAX

Pathways

Angiogenesis
Translation
Localization
Regeneration
Cell Cycle
Secretion
Cell Adhesion
Cell Activation
Cellular Homeostasis
Fibroblast Proliferation
Interferon-gamma Production
Immune Response

T Cell Homeostasis
Interleukin-4 Production
Glucose Homeostasis
Sensitization
Cell Death
Wound Healing
Myoblast Differentiation

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

Biologically Active Proteins
Cytokine Research

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AIMP1

References

PMID: 7929199 by Kao J., et al. Characterization of a novel tumor-derived cytokine. Endothelial- monocyte activating polypeptide II.

PMID: 24312579 by Kim K., et al. Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex.