Product Info Summary
SKU: | M01669 |
---|---|
Size: | 50 µl |
Reactive Species: | Human |
Host: | Mouse |
Application: | WB |
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Product info
Product Name
Anti-ABCB4 Antibody
View all MDR3/ABCB4 Antibodies
SKU/Catalog Number
M01669
Size
50 µl
Description
Boster Bio Anti-ABCB4 Antibody (Catalog # M01669). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-ABCB4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01669)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1808CT346.21.23
Isotype
IgG1,k
Immunogen
This ABCB4 antibody is generated from a mouse immunized with a recombinant protein of human ABCB4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01669 is reactive to ABCB4 in Human
Reconstitution
Calculated molecular weight
141523 Da
Background of MDR3/ABCB4
Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01669 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:4000
Validation Images & Assay Conditions
Click image to see more details
Anti-ABCB4 Antibody at 1:4000 dilution + MCF-7 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 142 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For ABCB4 (Source: Uniprot.org, NCBI)
Gene Name
ABCB4
Full Name
Phosphatidylcholine translocator ABCB4
Weight
141523 Da
Superfamily
ABC transporter superfamily
Alternative Names
Multidrug resistance protein 3, 3.6.3.44, ATP-binding cassette sub-family B member 4, P-glycoprotein 3, ABCB4, MDR3, PGY3 ABCB4 ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3 ATP binding cassette subfamily B member 4 phosphatidylcholine translocator ABCB4|ATP-binding cassette sub-family B member 4|ATP-binding cassette, sub-family B (MDR/TAP), member 4|P-glycoprotein 3|P-glycoprotein-3/multiple drug resistance-3|multidrug resistance protein 3|multiple drug resistance 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ABCB4, check out the ABCB4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ABCB4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ABCB4 Antibody (M01669)
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