This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Putative Polycomb group protein ASXL2.
PcG proteins aren't required to initiate repression, but to maintain it through later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity).
Human | |
---|---|
Gene Name: | ASXL2 |
Uniprot: | Q76L83 |
Entrez: | 55252 |
Belongs to: |
---|
Asx family |
additional sex combs like 2 (Drosophila); Additional sex combs-like protein 2; ASXH2polycomb group protein ASXH2; FLJ10898; KIAA1685DKFZp686C1968; putative Polycomb group protein ASXL2
Mass (kDA):
153.82 kDA
Human | |
---|---|
Location: | 2p23.3 |
Sequence: | 2; NC_000002.12 (25733753..25878487, complement) |
Nucleus.
PMID: 21047783 by Park U.H., et al. Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator- activated receptor {gamma}.
PMID: 27693232 by Shashi V., et al. De novo truncating variants in ASXL2 are associated with a unique and recognizable clinical phenotype.