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ADP-ribosylation factor 6 Antibodies
AND ARF6 ELISA kits, ADP-ribosylation factor 6 Proteins
Many biological assays use antibodies to detect ADP-ribosylation factor 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADP-ribosylation factor 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADP-ribosylation factor 6 antibodies...
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ARF6 Infographic by Boster Bio
All ARF6 Products
Product
Figures
Specificity
Applications
Price
Anti-ARF6 Antibody Picoband®
17 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9987
100 μg/vial
Cat # PB9987
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$449
Cat # A00927
0.1 mg
Cat # A00927
0.1 mg
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00927-2
100 μg/vial
Cat # A00927-2
100 μg/vial
ARF6 Overview
Facts about ADP-ribosylation factor 6.
ADP-ribosylation factor 6 (ARF6)
Required for normal conclusion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity).
Involved in the regulation of dendritic spine growth, contributing to the regulation of dendritic branching and filopodia extension (PubMed:14978216). Plays an essential role in membrane trafficking, during junctional remodeling and epithelial polarization.
Gene Information
| Human | |
|---|---|
| Gene Name: | ARF6 |
| Uniprot: | P62330 |
| Entrez: | 382 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
ADP-ribosylation factor 6; DKFZp564M0264
Molecular Weight
Mass (kDA):
20.082 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q21.3 |
| Sequence: | 14; NC_000014.9 (49893082..49897054) |
Tissue Specificity
Ubiquitous, with higher levels in heart, substantia nigra, and kidney.
Subcellular Localizations
Cytoplasm, cytosol. Cell membrane; Lipid-anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane; Lipid-anchor. Cell projection, filopodium membrane; Lipid-anchor. Cell projection, ruffle. Cleavage furrow. Midbody, Midbody ring. Early endosome membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Distributed uniformly on the plasma membrane, as well as throughout the cytoplasm during metaphase. Subsequently concentrated at patches in the equatorial region at the onset of cytokinesis, and becomes distributed in the equatorial region concurrent with cl
Diseases
- Tissue Adhesions
- Cell Invasion
- Malignant Neoplasms
- Neoplasms
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Cholera
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Nervousness
- Protrusion
- Tumor Angiogenesis
- Carcinoma
Interacting Proteins
- APBB1
- ARFIP2
- ATP6V1C1
- GGA3
- KIF23
- SPAG9
Pathways
- Endocytosis
- Localization
- Transport
- Cell Migration
- Cell Motility
- Exocytosis
- Endocytic Recycling
- Cell Adhesion
- Secretion
- Cytokinesis
- Phagocytosis
- Rna Interference
- Clathrin-mediated Endocytosis
PTMs
- Ribosylation
- Phosphorylation
- Myristoylation
- Cleavage
- Prenylation
Research Areas
- Cell Cycle and Replication
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARF6
bosterbio.com/bosterbio-gene-info-cards/ARF6
References
PMID: 1993656 by Tsuchiya M., et al. Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.
PMID: 14659046 by Lebeda R.A., et al. Sequence, genomic organization, and expression of the human ADP- ribosylation factor 6 (ARF6) gene: a class III ARF.