Amphiphysin Antibodies

AND AMPH ELISA kits, Amphiphysin Proteins

Many biological assays use antibodies to detect Amphiphysin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Amphiphysin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Amphiphysin antibodies...

We validate the specificity of these antibodies to Amphiphysin by testing them on tissues known to express AMPH positively and negatively. Browse below to find the AMPH antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AMPH Infographic by Boster Bio

All AMPH Products

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Product

Figures

Specificity

Applications

Price

Anti-Amphiphysin AMPH Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A02364
100ul

Amphiphysin (AMPH) (NM_001635) Human Recombinant Protein

$1062
Cat # PROTP49418
20 µg

Anti-AMPH Antibody (Center)

Human

IHC-P, WB

$299
Cat # M02364
80 µl

Amphiphysin (AMPH) (NM_001635) Human Over-expression Lysate

Human

$628
Cat # LS000273
100 µg

Anti-Amphiphysin/AMPH Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02364-1
100 µg/vial

AMPH Overview

Facts about Amphiphysin.

AMPH 3D structure. Source: alphafold

Amphiphysin (AMPH)

May participate in mechanisms of regulated exocytosis in synapses and specific endocrine cell types. May control the properties of the membrane associated cytoskeleton.

Gene Information

Human
Gene Name:	AMPH
Uniprot:	P49418
Entrez:	273

Family

Belongs to:

No superfamily

Alternative Names

AMPH; AMPH1; amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); amphiphysin I; Amphiphysin

Molecular Weight

Mass (kDA):
76.257 kDA

Genomic Context


Human

Location:	7p14.1
Sequence:	7; NC_000007.14 (38383694..38631567, complement)

Tissue Specificity

Neurons, certain endocrine cell types and spermatocytes.

Subcellular Localizations

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.

Diseases

Stereotyped Behavior
Schizophrenia
Neurotoxicity Syndromes
Stereotypic Movement Disorder
Substance Withdrawal Syndrome
Psychotic Disorders
Depressive Disorder
Nervousness
Pcp - Hallucinogen-related Disorder
Impairment (finding)
Nerve Degeneration

Bipolar Disorder
Candidiasis
Mycoses
Attention Deficit Hyperactivity Disorder
Aspergillosis
Stress, Psychological

Interacting Proteins

ARL16
Clta
DEUP1
Necap1
Necap1

PPP3CC
TERF1
Tfap2a

Pathways

Sensitization
Locomotion
Prepulse Inhibition
Transport
Reflex
Habituation
Response To Amphetamine
Endocytosis
Startle Response
Secretion
Dopamine Uptake
Innervation
Hypersensitivity

Localization
Cognition
Brain Development
Feeding Behavior
Mating
Pathogenesis
Inflammatory Response

PTMs

Phosphorylation
Cleavage
Oxidation
Dephosphorylation
Biotinylation
Reduction
Methylation

Demethylation
Phosphorothioation
Hydroxylation
Decarboxylation
Ubiquitination
Glycosylation
Acetylation

Research Areas

Cancer
Immune System Diseases
Immunology
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AMPH

References

PMID: 8076697 by David C., et al. Autoimmunity in stiff-man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161.

PMID: 7757077 by Yamamoto R., et al. Primary structure of human amphiphysin, the dominant autoantigen of paraneoplastic stiff-man syndrome, and mapping of its gene (AMPH) to chromosome 7p13-p14.