Apolipoprotein C-III Antibodies

AND APOC3 ELISA kits, Apolipoprotein C-III Proteins

Many biological assays use antibodies to detect Apolipoprotein C-III, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein C-III in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein C-III antibodies...

We validate the specificity of these antibodies to Apolipoprotein C-III by testing them on tissues known to express APOC3 positively and negatively. Browse below to find the APOC3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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APOC3 Infographic by Boster Bio

All APOC3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Apolipoprotein CIII/APOC3 Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse

Flow Cytometry, IHC, WB

$370
Cat # PB10043
100 μg/vial

Anti-APOLIPOPROTEINC-III APOC3 Antibody

4 Q&As

Human

IHC

$1709
Cat # A01416
1mg

Anti-APOC3 Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M01416
100 μl/vial

Apolipoprotein CIII (APOC3) (NM_000040) Human Over-expression Lysate

Human

$628
Cat # LS000345
100 µg

APOC3 Overview

Facts about Apolipoprotein C-III.

APOC3 3D structure. Source: alphafold

Apolipoprotein C-III (APOC3)

Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806).

Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) secretion and assembly; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806).

Gene Information

Human
Gene Name:	APOC3
Uniprot:	P02656
Entrez:	345

Family

Belongs to:

apolipoprotein C3 family

Alternative Names

APOC3; APOCIII; apo-CIII; apoC-III; Apolipoprotein C3; apolipoprotein C-III; MGC150353

Molecular Weight

Mass (kDA):
10.852 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (116829907..116833072)

Tissue Specificity

Liver.

Subcellular Localizations

Secreted.

Diseases

Diabetes Mellitus
Cardiovascular Diseases
Coronary Heart Disease
Diabetes Mellitus, Non-insulin-dependent
Obesity
Heart Diseases
Dysequilibrium Syndrome
Dyslipidemias
Insulin Resistance
Coronary Artery Disease
Atherosclerosis
Hyperlipidemia
Liver Diseases

Fatty Liver
Metabolic Syndrome X
Arteriosclerosis
Nonalcoholic Fatty Liver Disease
Combined Hyperlipidaemia
5,10-methylenetetrahydrofolate Reductase Deficiency
Cholangiocarcinoma

Pathways

Secretion
Pathogenesis
Transport
Lipid Transport
Platelet Aggregation
Flight
Lipid Homeostasis
Localization
Glucose Homeostasis
Cholesterol Efflux
Lipid Binding
Cognition
Aging

Immune Response
Inflammatory Response
Translation
Cell Cycle
Liver Regeneration
Cholesterol Transport
Triglyceride Homeostasis

PTMs

Phosphorylation
Cleavage

Glycosylation
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOC3

References

PMID: 6439535 by Protter A.A., et al. Isolation and sequence analysis of the human apolipoprotein CIII gene and the intergenic region between the apo AI and apo CIII genes.

PMID: 6548954 by Levy-Wilson B., et al. Isolation and DNA sequence of full-length cDNA for human preapolipoprotein CIII.

1 Publications of Boster Apolipoprotein C-III Antibodies & ELISA Kits

PubMed ID: 31985029, Chen H,Wu M,Jiang W,Liu X,Zhang J,Yu C.iTRAQ‑based quantitative proteomics ana...

*More publications can be found for each product on its corresponding product page