AP5Z1 Antibodies

AND AP5Z1 ELISA kits, AP5Z1 Proteins

Many biological assays use antibodies to detect AP5Z1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP5Z1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP5Z1 antibodies...

We validate the specificity of these antibodies to AP5Z1 by testing them on tissues known to express AP5Z1 positively and negatively. Browse below to find the AP5Z1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP5Z1 Infographic by Boster Bio

All AP5Z1 Products

Product

Figures

Specificity

Applications

Price

SPG48 (AP5Z1) (NM_014855) Human Over-expression Lysate

Human

$960
Cat # LS009907
100 µg

AP5Z1 Overview

Facts about AP-5 complex subunit zeta-1.

AP5Z1 3D structure. Source: alphafold

AP-5 complex subunit zeta-1 (AP5Z1)

Included in AP-5, a probable fifth adaptor protein complex it can be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair.

Gene Information

Human
Gene Name:	AP5Z1
Uniprot:	O43299
Entrez:	9907

Family

Belongs to:

No superfamily

Alternative Names

KIAA0415; SPG48hypothetical protein LOC9907

Molecular Weight

Mass (kDA):
88.605 kDA

Genomic Context


Human

Location:	7p22.1
Sequence:	7; NC_000007.14 (4775623..4794397)

Subcellular Localizations

Cytoplasm. Nucleus. By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic.

Diseases

Spastic paraplegia 48, autosomal recessive (SPG48)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP5Z1

References

PMID: 20613862 by Slabicki M., et al. A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.

PMID: 22022230 by Hirst J., et al. The fifth adaptor protein complex.