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- Table of Contents
Facts about ADAM DEC1.
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Human | |
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Gene Name: | ADAMDEC1 |
Uniprot: | O15204 |
Entrez: | 27299 |
Belongs to: |
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No superfamily |
A disintegrin and metalloproteinase domain-like protein decysin-1; ADAM DEC1; ADAM-like protein decysin-1; ADAM-like, decysin 1; decysin; disintegrin protease; EC 3.4.24.-; FLJ79219; M12.219
Mass (kDA):
52.775 kDA
Human | |
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Location: | 8p21.2 |
Sequence: | 8; NC_000008.11 (24384285..24406013) |
Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.
Secreted.
PMID: 9271581 by Mueller C.G.F., et al. Polymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cells.
PMID: 14632642 by Fritsche J., et al. Inverse regulation of the ADAM-family members, decysin and MADDAM/ADAM19 during monocyte differentiation.