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- Table of Contents
Facts about Long-chain-fatty-acid--CoA ligase 1.
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Human | |
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Gene Name: | ACSL1 |
Uniprot: | P33121 |
Entrez: | 2180 |
Belongs to: |
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ATP-dependent AMP-binding enzyme family |
ACS1LACS 2; Acyl-CoA synthetase 1; acyl-CoA synthetase long-chain family member 1; EC 6.2.1; FACL1EC 6.2.1.3; fatty-acid-Coenzyme A ligase, long-chain 1; LACS 1; LACSlong-chain 2; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; Long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; long-chain-fatty-acid--CoA ligase 1; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1
Mass (kDA):
77.943 kDA
Human | |
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Location: | 4q35.1 |
Sequence: | 4; NC_000004.12 (184755595..184826593, complement) |
Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
PMID: 1607358 by Abe T., et al. Human long-chain acyl-CoA synthetase: structure and chromosomal location.
PMID: 8584017 by Ghosh B., et al. Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression.