ATP2B3 Antibodies

AND ATP2B3 ELISA kits, ATP2B3 Proteins

Many biological assays use antibodies to detect ATP2B3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP2B3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP2B3 antibodies...

We validate the specificity of these antibodies to ATP2B3 by testing them on tissues known to express ATP2B3 positively and negatively. Browse below to find the ATP2B3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATP2B3 Infographic by Boster Bio

All ATP2B3 Products

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Product

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Specificity

Applications

Price

Anti-AT2B3 ATP2B3 Antibody

Human, Rat

ELISA, WB

$380
Cat # A05418
100ul

Anti-ATP2B3 Antibody (C-term)

Human

IF, WB

$299
Cat # M05418
80 µl

ATP2B3 Overview

Facts about Plasma membrane calcium-transporting ATPase 3.

ATP2B3 3D structure. Source: alphafold

Plasma membrane calcium-transporting ATPase 3 (ATP2B3)

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. .

Gene Information

Human
Gene Name:	ATP2B3
Uniprot:	Q16720
Entrez:	492

Family

Belongs to:

cation transport ATPase (P-type) (TC 3.A.3) family

Alternative Names

ATPase, Ca++ transporting, plasma membrane 3; EC 3.6.3; EC 3.6.3.8; Plasma membrane calcium ATPase isoform 3; plasma membrane calcium ATPase; Plasma membrane calcium pump isoform 3; plasma membrane calcium-transporting ATPase 3; PMCA3a; PMCA3plasma membrane calcium pump

Molecular Weight

Mass (kDA):
134.197 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (153517677..153582929)

Tissue Specificity

Highly expressed in the cerebellum, particulary in the presynaptic terminals of parallel fibers- Purkinje neurons. Isoform XE and isoform XB are the most abundant isoforms and are detected at low levels in brain and fetal skeletal muscle. The other isoforms are only found at lower levels and not in fetal tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Neuromuscular Diseases
Cell Transformation, Neoplastic
Weakness
Malignant Neoplasm Of Breast
Muscle Hypotonia
Myopathy
Cataract
Fracture
Malignant Neoplasms
Corneal Diseases
Generalized Muscle Weakness

Nervousness
Attention Deficit Hyperactivity Disorder
Mammary Neoplasms
Muscle Weakness
Hyperplasia
Congenital Structural Myopathy

Pathways

Transport
Localization
Regeneration
Reverse Transcription
Lactation
Molting Cycle

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP2B3

References

PMID: 8765088 by Brown B., et al. Primary structure of human plasma membrane Ca(2+)-ATPase isoform 3.

PMID: 8187550 by Wang M.G., et al. Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.