Product Info Summary
SKU: | A03109 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-AIMP1 Antibody
View all EMAP-II/AIMP1 Antibodies
SKU/Catalog Number
A03109
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-AIMP1 Antibody (Catalog # A03109). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
AIMP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-AIMP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03109)
Host
Rabbit
Contents
AIMP1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
AIMP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AIMP1. The immunogen is located within amino acids 240 - 290 of AIMP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
AIMP1 antibody is human, mouse and rat reactive. At least two isoforms of AIMP1 are known to exist; this antibody will recognize both isoforms. AIMP1 antibody is predicted to not cross-react with AIMP2.
Reactive Species
A03109 is reactive to AIMP1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
34353 MW
Background of EMAP-II/AIMP1
AIMP1 (Endothelial monocyte-activating polypeptide II, EMAP2) is a proinflammatory cytokine for monocytes and granulocytes (1). It is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing (1,2). AIMP1 was identified as one of three auxiliary factors of the mammalian aminoacyl tRNA synthetase (ARS) complex. It binds and facilitates the catalytic reaction of arginyl-tRNA synthetase (2,3). Recent studies show that CD23 plays an essential role in the AIMP1-induced immune response and might be a target in the treatment of inflammatory diseases (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03109 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
AIMP1 antibody can be used for detection of AIMP1 by Western blot at 1 μg/ml.
Antibody validated: Western Blot in human, mouse, and rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of AIMP1 in (A) human
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Immunohistochemistry of AIMP1 in mouse brain tissue with AIMP1 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For AIMP1 (Source: Uniprot.org, NCBI)
Gene Name
AIMP1
Full Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
Weight
34353 MW
Alternative Names
p43, HLD3, EMAP2, SCYE1, EMAPII, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, EMAP-2 AIMP1 EMAP2, EMAPII, HLD3, SCYE1, p43 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 aminoacyl tRNA synthase complex-interacting multifunctional protein 1|ARS-interacting multifunctional protein 1|endothelial monocyte-activating polypeptide 2|endothelial-monocyte activating polypeptide II|multisynthase complex auxiliary component p43|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AIMP1, check out the AIMP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AIMP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AIMP1 Antibody (A03109)
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