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- Table of Contents
Facts about Histone chaperone ASF1B.
Does not take part in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis.
Human | |
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Gene Name: | ASF1B |
Uniprot: | Q9NVP2 |
Entrez: | 55723 |
Belongs to: |
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ASF1 family |
ASF1 silencing function 1 homolog B (S. cerevisiae); CCG1-interacting factor A-II; CIA-II; FLJ10604; hAsf1; hAsf1b; hCIA-II; histone chaperone ASF1B; silencing function protein 1 homolog B
Mass (kDA):
22.434 kDA
Human | |
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Location: | 19p13.12 |
Sequence: | 19; NC_000019.10 (14119512..14136589, complement) |
Highly expressed in testis and at lower levels in colon, small intestine and thymus.
Nucleus.
PMID: 11470414 by Sillje H.H.W., et al. Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.
PMID: 12842904 by Umehara T., et al. Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis.