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- Table of Contents
Facts about Plasma membrane calcium-transporting ATPase 4.
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Human | |
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Gene Name: | ATP2B4 |
Uniprot: | P23634 |
Entrez: | 493 |
Belongs to: |
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cation transport ATPase (P-type) (TC 3.A.3) family |
ATP2B2plasma membrane calcium ATPase; ATPase, Ca++ transporting, plasma membrane 4; DKFZp686G08106; DKFZp686M088; EC 3.6.3; EC 3.6.3.8; Matrix-remodeling-associated protein 1; matrix-remodelling associated 1; MXRA1; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 4; PMCA4b; PMCA4PMCA4x; sarcolemmal calcium pump
Mass (kDA):
137.92 kDA
Human | |
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Location: | 1q32.1 |
Sequence: | 1; NC_000001.11 (203626787..203744081) |
Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex.
Cell membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
PMID: 2137451 by Strehler E.E., et al. Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane.
PMID: 1531651 by Brandt P., et al. Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.