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- Table of Contents
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 9.
Cleaves the large aggregating proteoglycans, aggrecan (at the'1838-Glu-
.Human | |
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Gene Name: | ADAMTS9 |
Uniprot: | Q9P2N4 |
Entrez: | 56999 |
Belongs to: |
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No superfamily |
ADAM metallopeptidase with thrombospondin type 1 motif, 9; ADAMTS-9,9; FLJ42955
Mass (kDA):
216.491 kDA
Human | |
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Location: | 3p14.1 |
Sequence: | 3; NC_000003.12 (64515654..64688000, complement) |
Highly expressed in all fetal tissues. Expressed in a number of adult tissues with highest expression in heart, placenta and skeletal muscle.
Secreted, extracellular space, extracellular matrix. Endoplasmic reticulum.
PMID: 10936055 by Clark M.E., et al. ADAMTS 9, a novel member of the ADAM-TS/Metallospondin gene family.
PMID: 12514189 by Somerville R.P., et al. Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.