AGR2 Antibodies

AND AGR2 ELISA kits, AGR2 Proteins

Many biological assays use antibodies to detect AGR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGR2 antibodies...

We validate the specificity of these antibodies to AGR2 by testing them on tissues known to express AGR2 positively and negatively. Browse below to find the AGR2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AGR2 Infographic by Boster Bio

All AGR2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Anterior Gradient 2/AGR2 Antibody Picoband®

4 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # A02922-2
100 μg/vial

Anti-AGR2/Ag 2 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02922
100 μl

Anti-AGR2 Antibody

Human

Flow Cytometry, IP, IHC, ICC, WB

$405
Cat # A02922
100ul

Mouse Agr2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO88312
Starting from 20ug

Human AG-2/AGR2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO95994
Starting from 20ug

AGR2 (NM_006408) Human Over-expression Lysate

Human

$628
Cat # LS010551
100 µg

AGR2 Overview

Facts about Anterior gradient protein 2 homolog.

AGR2 3D structure. Source: alphafold

Anterior gradient protein 2 homolog (AGR2)

Required for MUC2 post-transcriptional secretion and synthesis. May play a role in the production of mucus by intestinal cells (By similarity).

Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113).

Gene Information

Human
Gene Name:	AGR2
Uniprot:	O95994
Entrez:	10551

Family

Belongs to:

AGR family

Alternative Names

AG2; AG-2; AG2member 17; AGR2; anterior gradient 2 homolog (Xenopus laevis); anterior gradient homolog 2 (Xenopus laevis); GOB-4; hAG-2; HPC8; PDIA17; secreted cement gland homolog

Molecular Weight

Mass (kDA):
19.979 kDA

Genomic Context


Human

Location:	7p21.1
Sequence:	7; NC_000007.14 (16791811..16804999, complement)

Tissue Specificity

Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.

Subcellular Localizations

Secreted. Endoplasmic reticulum.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Adenocarcinoma
Mammary Neoplasms
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Malignant Paraganglionic Neoplasm
Cell Invasion
Neoplasm Invasiveness

Cell Transformation, Neoplastic
Tumor Progression
Malignant Neoplasm Of Pancreas
Hyperplasia
Mucinous Adenocarcinoma
Ovarian Neoplasm
Malignant Neoplasm Of Ovary

Interacting Proteins

CATSPER1
FABP2
KRT31
MUC2
NUP62CL

POM121
SGTB
UBQLN1
UBQLN2

Pathways

Cell Proliferation
Pathogenesis
Cell Migration
Localization
Regeneration
Secretion
Cell Differentiation
Drug Resistance
Cell Growth
Cell Cycle
Epithelial Cell Proliferation
Protein Folding
Rna Interference

Transport
Cell Adhesion
Endoplasmic Reticulum Localization
Cellular Senescence
Fertilization
Lung Development
Cytokine Secretion

PTMs

Phosphorylation

Glycosylation

Acetylation

Research Areas

Breast Cancer
Cancer
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGR2

References

PMID: 9790916 by Thompson D.A., et al. hAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines.

PMID: 12592373 by Fletcher G.C., et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.