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- Table of Contents
Facts about AKT-interacting protein.
Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade (By similarity).
Mouse | |
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Gene Name: | Aktip |
Uniprot: | Q64362 |
Entrez: | 14339 |
Belongs to: |
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ubiquitin-conjugating enzyme family |
AKT interacting protein; AKT-interacting protein; FLJ13258; FT1; FTSfused toes homolog (mouse); fused toes (mouse) homolog; fused toes homolog; Fused toes protein homolog
Mass (kDA):
32.942 kDA
Mouse | |
---|---|
Location: | 8 C4|8 44.25 cM |
Sequence: | 8; |
Ubiquitous. Highest expression in kidney, testis and brain and lowest in spleen and liver.
PMID: 9383278 by Lesche R., et al. Ft1, a novel gene related to ubiquitin conjugating enzymes, is deleted in the Fused toes mouse mutation.
PMID: 7956835 by van der Hoeven F., et al. Programmed cell death is affected in the novel mouse mutant Fused toes (Ft).