ASIC4 Antibodies

AND ASIC4 ELISA kits, ASIC4 Proteins

Many biological assays use antibodies to detect ASIC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ASIC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ASIC4 antibodies...

We validate the specificity of these antibodies to ASIC4 by testing them on tissues known to express ASIC4 positively and negatively. Browse below to find the ASIC4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASIC4 Infographic by Boster Bio

All ASIC4 Products

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ACCN4 (ASIC4) (NM_182847) Human Recombinant Protein

$813
Cat # PROTQ96FT7
20 µg

ACCN4 (ASIC4) (NM_182847) Human Over-expression Lysate

Human

$628
Cat # LS055515
100 µg

ASIC4 Overview

Facts about Acid-sensing ion channel 4.

ASIC4 3D structure. Source: alphafold

Acid-sensing ion channel 4 (ASIC4)

Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.

Gene Information

Human
Gene Name:	ASIC4
Uniprot:	Q96FT7
Entrez:	55515

Family

Belongs to:

amiloride-sensitive sodium channel (TC 1.A.6) family

Alternative Names

Acid-sensing ion channel 4; amiloride-sensitive cation channel 4, pituitaryMGC17248; ASIC4MGC24860; BNAC4amiloride-sensitive cation channel 4; brain sodium channel 4

Molecular Weight

Mass (kDA):
70.105 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (219514170..219538772)

Tissue Specificity

Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Nervousness
Pain
Pituitary Diseases
Nerve Damage
Ischemia
Nerve Degeneration
Macule
Dystonia Disorders
Nervous System Disorder
Paroxysmal Dystonia
Hyperalgesia

Neuralgia
Inflammation
Febrile Convulsions
Movement Disorders
Paroxysmal Nonkinesigenic Dyskinesia
Choreoathetosis

Pathways

Synaptic Transmission
Localization
Osteoclast Differentiation
Cell Migration
Chemotaxis
Muscle Cell Migration
Smooth Muscle Cell Migration
Immune Response

Endocytosis
Wound Healing

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASIC4

References

PMID: 10852210 by Gruender S., et al. A new member of acid-sensing ion channels from pituitary gland.

PMID: 11571555 by Gruender S., et al. Acid-sensing ion channel (ASIC) 4 gene: physical mapping, genomic organisation, and evaluation as a candidate for paroxysmal dystonia.