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- Table of Contents
Facts about Rho GTPase-activating protein 9.
Has a role in regulating adhesion of hematopoietic cells into the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Human | |
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Gene Name: | ARHGAP9 |
Uniprot: | Q9BRR9 |
Entrez: | 64333 |
Belongs to: |
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No superfamily |
FLJ16525,10C; MGC1295; RGL1; Rho GTPase activating protein 9; rho GTPase-activating protein 9; Rho-type GTPase-activating protein 9
Mass (kDA):
83.26 kDA
Human | |
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Location: | 12q13.3 |
Sequence: | 12; NC_000012.12 (57472262..57488824, complement) |
Predominantly expressed in peripheral blood leukocytes, spleen, and thymus.
PMID: 11396949 by Furukawa Y., et al. Isolation of a novel human gene, ARHGAP9, encoding a rho-GTPase activating protein.
PMID: 17339315 by Ceccarelli D.F., et al. Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9.