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- Table of Contents
Facts about Protein ELYS.
Also required for the localization of this Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis. .
Human | |
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Gene Name: | AHCTF1 |
Uniprot: | Q8WYP5 |
Entrez: | 25909 |
Belongs to: |
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ELYS family |
AT hook containing transcription factor 1; ELYS transcription factor like protein TMBS62; ELYS transcription factor-like protein TMBS62; ELYS; MST108; MSTP108; protein ELYS; putative AT-hook-containing transcription factor 1; TMBS62
Mass (kDA):
252.498 kDA
Human | |
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Location: | 1q44 |
Sequence: | 1; NC_000001.11 (246839098..246931948, complement) |
Cytoplasm. Nucleus. Nucleus envelope. Nucleus matrix. Chromosome, centromere, kinetochore. Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.
PMID: 11952839 by Kimura N., et al. Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues.
PMID: 17098863 by Rasala B.A., et al. ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division.