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- Table of Contents
Facts about ADP-ribose glycohydrolase ARH3.
Generates ADP-ribose from poly-(ADP-ribose), but doesn't hydrolyze ADP- ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the sole PAR hydrolyzing enzyme in mitochondria (By similarity).
Mouse | |
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Gene Name: | Adprhl2 |
Uniprot: | Q8CG72 |
Entrez: | 100206 |
Belongs to: |
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ADP-ribosylglycohydrolase family |
[Protein ADP-ribosylarginine] hydrolase-like protein 2; ADP-ribosylhydrolase 3; ADP-ribosylhydrolase like 2; ARH3EC 3.2.1.143; FLJ20446; poly(ADP-ribose) glycohydrolase ARH3; protein ADP-ribosylarginine hydrolase-like protein 2
Mass (kDA):
39.414 kDA
Mouse | |
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Location: | 4|4 D2.2 |
Sequence: | 4; |
Ubiquitous.
PMID: 12070318 by Glowacki G., et al. The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.
PMID: 16278211 by Oka S., et al. Identification and characterization of a mammalian 39-kDa poly(ADP- ribose) glycohydrolase.