ATP8B4 Antibodies

AND ATP8B4 ELISA kits, ATP8B4 Proteins

Many biological assays use antibodies to detect ATP8B4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP8B4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP8B4 antibodies...

We validate the specificity of these antibodies to ATP8B4 by testing them on tissues known to express ATP8B4 positively and negatively. Browse below to find the ATP8B4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATP8B4 Infographic by Boster Bio

All ATP8B4 Products

Product

Figures

Specificity

Applications

Price

ATP8B4 (NM_024837) Human Over-expression Lysate

Human

$960
Cat # LS079895
100 µg

ATP8B4 Overview

Facts about Probable phospholipid-transporting ATPase IM.

ATP8B4 3D structure. Source: alphafold

Probable phospholipid-transporting ATPase IM (ATP8B4)

Part of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids in the outer to the inner leaflet of different membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation appears also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable).

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Gene Information

Human
Gene Name:	ATP8B4
Uniprot:	Q8TF62
Entrez:	79895

Family

Belongs to:

cation transport ATPase (P-type) (TC 3.A.3) family

Alternative Names

ATPase class I type 8B member 4; ATPase, class I, type 8B, member 4; ATPIM; EC 3.6.3; EC 3.6.3.1; FLJ25418; KIAA1939; potential phospholipid-transporting ATPase IM; probable phospholipid-transporting ATPase IM

Molecular Weight

Mass (kDA):
135.868 kDA

Genomic Context


Human

Location:	15q21.2
Sequence:	15; NC_000015.10 (49858238..50181851, complement)

Tissue Specificity

Ubiquitously expressed at moderate levels.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Golgi apparatus.

Diseases

Cholestasis
Multiple Myeloma
Intrahepatic Cholestasis
Liver Failure
Impaired Cognition
Cytogenetic Abnormality
Alzheimer's Disease

Dysequilibrium Syndrome

Pathways

Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP8B4

References

PMID: 20947505 by van der Velden L.M., et al. Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.

PMID: 20961850 by Bryde S., et al. CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.