Aquaporin-5 Antibodies

AND AQP5 ELISA kits, Aquaporin-5 Proteins

Many biological assays use antibodies to detect Aquaporin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aquaporin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aquaporin-5 antibodies...

We validate the specificity of these antibodies to Aquaporin-5 by testing them on tissues known to express AQP5 positively and negatively. Browse below to find the AQP5 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AQP5 Infographic by Boster Bio

All AQP5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Aquaporin 5/AQP5 Antibody Picoband®

5 Citations

Mouse, Rat

IHC, WB

$370
Cat # PA1230
100 μg/vial

Anti-AQP5 Rabbit Monoclonal Antibody

5 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # M03085
100 μl

Anti-Aquaporin 5/AQP5 Antibody Picoband®

1 Citations

Human, Mouse, Rat

IHC, WB

$370
Cat # A03085
100 μg/vial

Anti-AQP5 (Y243) Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03085Y243
100ul

Aquaporin 5 (AQP5) (NM_001651) Human Over-expression Lysate

Human

$628
Cat # LS000362
100 µg

AQP5 Overview

Facts about Aquaporin-5.

AQP5 3D structure. Source: alphafold

Aquaporin-5 (AQP5)

Types a water-specific channel. Implicated in the creation of saliva, tears, and pulmonary secretions.

Required for TRPV4 activation by hypotonicity (PubMed:16571723). Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723).

Gene Information

Human
Gene Name:	AQP5
Uniprot:	P55064
Entrez:	362

Family

Belongs to:

MIP/aquaporin (TC 1.A.8) family

Alternative Names

AQP-5; aquaporin 5; aquaporin-5

Molecular Weight

Mass (kDA):
28.292 kDA

Genomic Context


Human

Location:	12q13.12
Sequence:	12; NC_000012.12 (49961855..49965682)

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.

Diseases

Salivary Gland Diseases
Edema
Lung Injury
Sjogren's Syndrome
Malignant Neoplasms
Inflammation
Neoplasms
Corneal Diseases
Pulmonary Edema
Xerostomia
Acute Lung Injury
Neoplasm Metastasis

Lung Diseases
Diabetes Mellitus
Carcinoma
Fibrosis
Mucinous Adenocarcinoma
Hyperplasia
Pneumonia

Interacting Proteins

HNRNPK
KRT31
KRT40
MDFI
NOTCH2NL

Pathways

Transport
Secretion
Localization
Water Transport
Fluid Transport
Water Homeostasis
Cell Proliferation
Pathogenesis
Lung Development
Saliva Secretion
Cell Differentiation
Cell Migration
Cellular Localization

Transdifferentiation
Exocytosis
Reverse Transcription
Cell Growth
Epithelial Cell Differentiation
Gland Development
Regeneration

PTMs

Phosphorylation
Cleavage
Demethylation
Methylation

Glycosylation
Dephosphorylation
Biotinylation
Reduction

Acetylation

Research Areas

Cancer
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AQP5

References

PMID: 8621489 by Lee M.D., et al. The human aquaporin-5 gene. Molecular characterization and chromosomal localization.

PMID: 16571723 by Liu X., et al. A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.

5 Publications of Boster Aquaporin-5 Antibodies & ELISA Kits

PubMed ID: 10.1080/09291016.2021.2007329, Expression of AQP1, AQP3, AQP4 and AQP5 in upper respiratory tract of buffaloes ...
PubMed ID: 10.1016/j.ydbio.2017.07.018, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular matur...
PubMed ID: 10.1016/j.jtherbio.2020.102727, Seasonal effect in expression of AQP1, AQP3 and AQP5 in skin of Murrah buffaloes
PubMed ID: 26668595, Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by sti...
PubMed ID: 28811219, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular matur...

*More publications can be found for each product on its corresponding product page