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- Table of Contents
Facts about Histone chaperone ASF1A.
Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. .
Human | |
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Gene Name: | ASF1A |
Uniprot: | Q9Y294 |
Entrez: | 25842 |
Belongs to: |
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ASF1 family |
ASF1 silencing function 1 homolog A (S. cerevisiae); CCG1-interacting factor A; CIACGI-98; DKFZP547E2110; hAsf1; hAsf1a; hCIA; histone chaperone ASF1A; HSPC146; silencing function 1A; silencing function protein 1 homolog A
Mass (kDA):
22.969 kDA
Human | |
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Location: | 6q22.31 |
Sequence: | 6; NC_000006.12 (118894152..118909171) |
Ubiquitously expressed.
Nucleus.
PMID: 10759893 by Munakata T., et al. A human homologue of yeast anti-silencing factor has histone chaperone activity.
PMID: 11470414 by Sillje H.H.W., et al. Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.