Adhfe1 Antibodies

AND Adhfe1 ELISA kits, Adhfe1 Proteins

Many biological assays use antibodies to detect Adhfe1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adhfe1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adhfe1 antibodies...

We validate the specificity of these antibodies to Adhfe1 by testing them on tissues known to express Adhfe1 positively and negatively. Browse below to find the Adhfe1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Adhfe1 Infographic by Boster Bio

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ADHFE1 (NM_144650) Human Over-expression Lysate

Human

$960
Cat # LS137872
100 µg

Adhfe1 Overview

Facts about Hydroxyacid-oxoacid transhydrogenase, mitochondrial.

Hydroxyacid-oxoacid transhydrogenase, mitochondrial (Adhfe1)

Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) into D-2- hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the creation of D-2-HG (By similarity).

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Gene Information

Mouse
Gene Name:	Adhfe1
Uniprot:	Q8R0N6
Entrez:	76187

Family

Belongs to:

iron-containing alcohol dehydrogenase family

Alternative Names

ADH8; alcohol dehydrogenase, iron containing, 1; EC 1.1.99.24; Fe-containing alcohol dehydrogenase; HOTmitochondrial; MGC48605

Molecular Weight

Mass (kDA):
49.937 kDA

Genomic Context


Mouse

Location:	1\|1 A2
Sequence:	1;

Tissue Specificity

Expressed in white and brown adipose tissues, liver, and kidney. Expression is differentiation-dependent during in vitro brown and white adipogenesis.

Diseases

Malignant Neoplasms
Obesity
Colorectal Neoplasms
Neuroblastoma
Adenoma
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Diabetes Mellitus
Insulin Sensitivity
Carcinoma

Diabetes Mellitus, Non-insulin-dependent
Metabolic Diseases
Neoplasms
Colorectal Cancer
Anoxia

Pathways

Methylation
Dna Methylation
Transport
Mitochondrial Fission
Fatty Acid Oxidation
Lipid Transport
Localization

Secretion

PTMs

Methylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Adhfe1

References

PMID: 17559793 by Kim J.Y., et al. Differentiation-dependent expression of Adhfe1 in adipogenesis.