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- Table of Contents
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 18.
Human | |
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Gene Name: | ADAMTS18 |
Uniprot: | Q8TE60 |
Entrez: | 170692 |
Belongs to: |
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No superfamily |
A disintegrin and metalloproteinase with thrombospondin motifs 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 21; ADAM metallopeptidase with thrombospondin type 1 motif, 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18; ADAMTS21; disintegrin and metalloprotease-like protein; EC 3.4.24.-; EC 3.4.24.82
Mass (kDA):
135.167 kDA
Human | |
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Location: | 16q23.1 |
Sequence: | 16; NC_000016.10 (77282128..77435034, complement) |
Expressed in fetal lung, liver, and kidney and in adult brain, prostate, submaxillary gland, and endothelium.
Secreted, extracellular space, extracellular matrix.
PMID: 11867212 by Cal S., et al. Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.
PMID: 21862674 by Aldahmesh M.A., et al. Identification of ADAMTS18 as a gene mutated in Knobloch syndrome.