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- Table of Contents
Facts about AT-rich interactive domain-containing protein 1B.
During neural development a change from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.
Human | |
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Gene Name: | ARID1B |
Uniprot: | Q8NFD5 |
Entrez: | 57492 |
Belongs to: |
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No superfamily |
6A3-5; ARID domain-containing protein 1B; AT rich interactive domain 1B (SWI1-like); BAF250B; BRG1-associated factor 250b; BRG1-binding protein ELD/OSA1; BRG1-binding protein hELD/OSA1; BRIGHT; DAN15P250R; ELD (eyelid)/OSA protein; ELD/OSA1; hOsa2; JPUT1; KDM5B; KIAA1235AT-rich interactive domain-containing protein 1B; Osa homolog 2; OSA2; p250R; PLU1; RBBP2H1A
Mass (kDA):
236.123 kDA
Human | |
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Location: | 6q25.3 |
Sequence: | 6; NC_000006.12 (156776026..157210779) |
Widely expressed with high levels in heart, skeletal muscle and kidney.
Nucleus.
PMID: 11734557 by Kato H., et al. SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.
PMID: 9804814 by Mangel L., et al. New 5'-(CGG)-3' repeats in the human genome.