Anti-Aquaporin 6/AQP6 Antibody Picoband®

Product Name

Anti-Aquaporin 6/AQP6 Antibody Picoband®

View all Aquaporin-6 Antibodies

SKU/Catalog Number

PA2092

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Aquaporin 6/AQP6 Antibody catalog # PA2092. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Aquaporin 6/AQP6 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2092)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2092 is reactive to AQP6 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

142 kDa

Calculated molecular weight

29370 MW

Background of Aquaporin-6

Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2092 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: U87 Cell, COLO320 Cell, MCF-7 Cell,
IHC: Human Placenta Tissue, Human Lung Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For AQP6 (Source: Uniprot.org, NCBI)

Alternative Names

Aquaporin-6;AQP-6;Aquaporin-2-like;Kidney-specific aquaporin;hKID;AQP6;AQP2L; AQP6 AQP2L, KID aquaporin 6 aquaporin-6|AQP-6|aquaporin 2-like, kidney specific|aquaporin-6, kidney specific|hKID|kidney-specific aquaporin

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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