ATP2B2 Antibodies

AND ATP2B2 ELISA kits, ATP2B2 Proteins

Many biological assays use antibodies to detect ATP2B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATP2B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATP2B2 antibodies...

We validate the specificity of these antibodies to ATP2B2 by testing them on tissues known to express ATP2B2 positively and negatively. Browse below to find the ATP2B2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATP2B2 Infographic by Boster Bio

All ATP2B2 Products

Product

Figures

Specificity

Applications

Price

Anti-ATP2B2 Antibody

Human, Mouse, Rat

$405
Cat # A03974
100ul

ATP2B2 Overview

Facts about Plasma membrane calcium-transporting ATPase 2.

ATP2B2 3D structure. Source: alphafold

Plasma membrane calcium-transporting ATPase 2 (ATP2B2)

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. .

Gene Information

Human
Gene Name:	ATP2B2
Uniprot:	Q01814
Entrez:	491

Family

Belongs to:

cation transport ATPase (P-type) (TC 3.A.3) family

Alternative Names

plasma membrane calcium-transporting ATPase 2; ATPase, Ca++ transporting, plasma membrane 2; PMCA2; PMCA2a; PMCA2i

Molecular Weight

Mass (kDA):
136.876 kDA

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (10324023..10707962, complement)

Tissue Specificity

Mainly expressed in brain cortex. Found in low levels in skeletal muscle, heart muscle, stomach, liver, kidney and lung. Isoforms containing segment B are found in brain cortex and at low levels in other tissues. Isoforms containing segments X and W are found at low levels in all tissues. Isoforms containing segment A and segment Z are found at low levels in skeletal muscle and heart muscle.

Subcellular Localizations

Cell junction, synapse. Cell membrane; Multi-pass membrane protein.

Diseases

Complete Hearing Loss
Ataxia
Malignant Neoplasms
Sclerosis
Multiple Sclerosis
Sensorineural Hearing Loss (disorder)
Malignant Neoplasm Of Breast
Mammary Neoplasms
Von Hippel-lindau Syndrome
Nervousness
Nerve Degeneration
Encephalomyelitis

Experimental Autoimmune Encephalomyelitis
Autistic Disorder
Autoimmune Reaction
Spinal Cord Injuries
Infertility
Endometriosis, Site Unspecified
Presbycusis

Interacting Proteins

CALCA
Dlg2
SCRIB

Pathways

Localization
Transport
Lactation
Secretory Pathway
Cell Death
Mammary Gland Involution
Exocytosis
Relaxation Of Vascular Smooth Muscle
Cell Proliferation
Associative Learning
Metaphase
Inner Ear Development
Mammary Gland Epithelial Cell Proliferation

Regeneration
Response To Risperidone
Reverse Transcription
Sperm Motility
Ear Development
Chromosome Organization
Mating

PTMs

Phosphorylation

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATP2B2

References

PMID: 1427863 by Brandt P., et al. Determination of the nucleotide sequence and chromosomal localization of the ATP2B2 gene encoding human Ca(2+)-pumping ATPase isoform PMCA2.

PMID: 8428366 by Latif F., et al. von Hippel-Lindau syndrome: cloning and identification of the plasma membrane Ca(++)-transporting ATPase isoform 2 gene that resides in the von Hippel-Lindau gene region.