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- Table of Contents
Facts about Rho GTPase-activating protein 10.
Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
Mouse | |
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Gene Name: | Arhgap10 |
Uniprot: | Q6Y5D8 |
Entrez: | 78514 |
Belongs to: |
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No superfamily |
Rho GTPase-activating protein 10
Mass (kDA):
89.366 kDA
Mouse | |
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Location: | 8|8 C1 |
Sequence: | 8; |
High levels of expression in brain, testes, liver, heart and kidney.
PMID: 11238453 by Ren X.-R., et al. Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
PMID: 15471851 by Koeppel M.A., et al. Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2.