ACSL4 Antibodies

AND ACSL4 ELISA kits, ACSL4 Proteins

Many biological assays use antibodies to detect ACSL4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACSL4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACSL4 antibodies...

We validate the specificity of these antibodies to ACSL4 by testing them on tissues known to express ACSL4 positively and negatively. Browse below to find the ACSL4 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACSL4 Infographic by Boster Bio

All ACSL4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-FACL4/ACSL4 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04372-2
100 μg/vial

FACL4 (ACSL4) (NM_022977) Human Recombinant Protein

$1249
Cat # PROTO60488
20 µg

Anti-FACL4/ACSL4 Antibody Picoband® (monoclonal, 4I7)

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M04372
100 μg/vial

Anti-FACL4 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M04372-1
100 μl/vial

Anti-FACL4/ACSL4 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A04372-3
100 μg/vial

FACL4 (ACSL4) (NM_004458) Human Over-expression Lysate

Human

$628
Cat # LS002182
100 µg

ACSL4 Overview

Facts about Long-chain-fatty-acid--CoA ligase 4.

ACSL4 3D structure. Source: alphafold

Long-chain-fatty-acid--CoA ligase 4 (ACSL4)

Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation through beta-oxidation. Preferentially uses arachidonate and eicosapentaenoate as substrates.

Gene Information

Human
Gene Name:	ACSL4
Uniprot:	O60488
Entrez:	2182

Family

Belongs to:

ATP-dependent AMP-binding enzyme family

Alternative Names

ACS4mental retardation, X-linked 68; acyl-CoA synthetase 4; acyl-CoA synthetase long-chain family member 4; EC 6.2.1.3; FACL4long-chain 4; LACS 4; LACS4MRX68; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; long-chain-fatty-acid--CoA ligase 4; mental retardation, X-linked 63; MRX63

Molecular Weight

Mass (kDA):
79.188 kDA

Genomic Context


Human

Location:	Xq23
Sequence:	X; NC_000023.11 (109641335..109733392, complement)

Subcellular Localizations

Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Fatty Liver
Diabetes Mellitus
Cell Transformation, Neoplastic
Carcinoma
Mammary Neoplasms
Liver Carcinoma
Steatosis
Muscle Hypotonia
Diabetes Mellitus, Non-insulin-dependent

Insulin Resistance
Nonalcoholic Fatty Liver Disease
Insulin Sensitivity
Autoimmunity
Malignant Tumor Of Colon
Neuromuscular Diseases

Pathways

Transport
Pathogenesis
Cell Proliferation
Fatty Acid Transport
Cell Adhesion
Gene Silencing
Endocytosis
Membrane Fusion
Energy Homeostasis
Methylation
Dna Replication

Reverse Transcription
Lipid Homeostasis
Lipid Storage
Segmentation
Glycolysis
Secretion

PTMs

Acetylation
Methylation

Oxidation
Acylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACSL4

References

PMID: 9598324 by Cao Y., et al. Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4).

PMID: 9480748 by Piccini M., et al. FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation.