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- Table of Contents
, No Gclids
ABCG1 Antibodies
AND ABCG1 ELISA kits, ABCG1 Proteins
Many biological assays use antibodies to detect ABCG1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCG1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCG1 antibodies...
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ABCG1 Infographic by Boster Bio
All ABCG1 Products
Product
Figures
Specificity
Applications
Price
Anti-ABCG1 Rabbit Monoclonal Antibody
2 Citations
Human, Rat
IF, IHC, ICC, WB
$370
Cat # M01227
100 μl
Cat # M01227
100 μl
ABCG1 Overview
Facts about ATP-binding cassette sub-family G member 1.
ATP-binding cassette sub-family G member 1 (ABCG1)
Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complicated.
Could also be involved in intracellular lipid transport procedures. The role in cellular lipid homeostasis may not be limited to macrophages.
Gene Information
| Human | |
|---|---|
| Gene Name: | ABCG1 |
| Uniprot: | P45844 |
| Entrez: | 9619 |
Family
| Belongs to: |
|---|
| ABC transporter superfamily |
Alternative Names
ABC transporter 8; ABC8; ABC8ATP-binding cassette sub-family G member 1; ABCG1; ATP-binding cassette transporter 8; ATP-binding cassette, sub-family G (WHITE), member 1; homolog of Drosophila white; MGC34313; white protein homolog (ATP-binding cassette transporter 8), 10ATP-binding cassette transporter member 1 of subfamily G; White protein homolog; WHITE1; WHT1
Molecular Weight
Mass (kDA):
75.592 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.3 |
| Sequence: | 21; NC_000021.9 (42199689..42304387) |
Tissue Specificity
Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.
Subcellular Localizations
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane. Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes.
Diseases
- Atherosclerosis
- Inflammation
- Cardiovascular Diseases
- Diabetes Mellitus
- Malignant Neoplasms
- Hypercholesterolemia
- Diabetes Mellitus, Non-insulin-dependent
- Arteriosclerosis
- Dental Plaque
- Alzheimer's Disease
- Obesity
- Dyslipidemias
Interacting Proteins
- ABCG4
Pathways
- Cholesterol Efflux
- Transport
- Cholesterol Transport
- Reverse Cholesterol Transport
- Cholesterol Homeostasis
- Secretion
- Lipid Homeostasis
- Pathogenesis
- Localization
- Excretion
- Cell Proliferation
- Lipid Transport
- Phospholipid Efflux
PTMs
- Phosphorylation
- Acetylation
- Cleavage
- Oxidation
- Hydroxylation
- Biotinylation
Research Areas
- ABC Transporters
- Cancer
- Cholesterol Metabolism
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCG1
bosterbio.com/bosterbio-gene-info-cards/ABCG1
References
PMID: 8659545 by Chen H.M., et al. Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3.
PMID: 10950923 by Berry A., et al. Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region.
3 Publications of Boster ABCG1 Antibodies & ELISA Kits
- PubMed ID: 26781796, Overexpression of C35 in breast carcinomas is associated with tumor progression ...
- PubMed ID: 21418611, Yan N, Ding T, Dong J, Li Y, Wu M. Lipids Health Dis. 2011 Mar 21;10:46. Doi: 10...
- PubMed ID: 25334019, Shang W, Yu X, Wang H, Chen T, Fang Y, Yang X, Zhou P, Nie F, Zhou Q, Zhou J. Mo...
*More publications can be found for each product on its corresponding product page