ARID4A Antibodies

AND ARID4A ELISA kits, ARID4A Proteins

Many biological assays use antibodies to detect ARID4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARID4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARID4A antibodies...

We validate the specificity of these antibodies to ARID4A by testing them on tissues known to express ARID4A positively and negatively. Browse below to find the ARID4A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARID4A Infographic by Boster Bio

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Retinoblastoma binding protein 1 (ARID4A) (NM_002892) Human Over-expression Lysate

Human

$960
Cat # LS005926
100 µg

ARID4A Overview

Facts about AT-rich interactive domain-containing protein 4A.

ARID4A 3D structure. Source: alphafold

AT-rich interactive domain-containing protein 4A (ARID4A)

DNA-binding protein that modulates activity of many transcription factors such as RB1 (retinoblastoma-associated protein) and AR (androgen receptor) (By similarity). May function as part of an mSin3A repressor complex (PubMed:14581478).

Has no intrinsic transcriptional activity (By similarity). Plays a role in the regulation of epigenetic alterations at the PWS/AS imprinting center close to the SNRPN promoter, where it might be part of a complicated with RB1 and ARID4B (By similarity).

Gene Information

Human
Gene Name:	ARID4A
Uniprot:	P29374
Entrez:	5926

Family

Belongs to:

No superfamily

Alternative Names

AT rich interactive domain 4A (RBP1-like); RBBP-1; RBP-1; RBP1ARID domain-containing protein 4A; retinoblastoma binding protein 1; Retinoblastoma-binding protein 1RBBP1AT-rich interactive domain-containing protein 4A

Molecular Weight

Mass (kDA):
142.752 kDA

Genomic Context


Human

Location:	14q23.1
Sequence:	14; NC_000014.9 (58298385..58373876)

Subcellular Localizations

Nucleus.

Diseases

Retinoblastoma
Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasms
Hyperplasia
Growth Arrest
Carcinoma
Metaplastic Cell Transformation
Tissue Adhesions
Mammary Neoplasms
Growth Retardation
Skin Neoplasms

Malignant Neoplasm Of Breast
Osteosarcoma
Leukemia
Melanoma
Neoplasms, Experimental
Lymphoma
Malignant Paraganglionic Neoplasm

Pathways

Cell Cycle
S Phase
Cell Proliferation
G1 Phase
Cell Growth
Dna Replication
Cell Cycle Arrest
Cell Death
Cell Division
Cell Differentiation
Localization
Oncogenesis
Mitosis

Hyperphosphorylation
Regulation Of Cell Cycle
Cell Adhesion
Induction Of Apoptosis
Senescence
Methylation
Regulation Of Cell Proliferation

PTMs

Phosphorylation
Methylation
Dephosphorylation

Cleavage
Ubiquitination
Reduction

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARID4A

References

PMID: 8414517 by Fattaey A.R., et al. Characterization of the retinoblastoma binding proteins RBP1 and RBP2.

PMID: 8455946 by Otterson G.A., et al. Alternative splicing of the RBP1 gene clusters in an internal exon that encodes potential phosphorylation sites.