This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
2 Citations 8 Q&As
Facts about Amphiregulin.
Ligand of the EGF receptor/EGFR.
Autocrine growth factor in addition to a mitogen for a broad selection of target cells including astrocytes, Schwann cells and fibroblasts..
Human | |
---|---|
Gene Name: | AREG |
Uniprot: | P15514 |
Entrez: | 374 |
Belongs to: |
---|
amphiregulin family |
Amphiregulin; AR; AREG; AREGB; Colorectum cell-derived growth factor; CRDGF; MGC13647; schwannoma-derived growth factor; SDGF
Mass (kDA):
27.895 kDA
Human | |
---|---|
Location: | 4q13.3 |
Sequence: | 4; NC_000004.12 (74445136..74455005) |
Membrane; Single-pass membrane protein.
PMID: 2325643 by Plowman G.D., et al. The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity.
PMID: 2466334 by Shoyab M., et al. Structure and function of human amphiregulin: a member of the epidermal growth factor family.
*More publications can be found for each product on its corresponding product page