This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial.
The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. .
Human | |
---|---|
Gene Name: | ALDH4A1 |
Uniprot: | P30038 |
Entrez: | 8659 |
Belongs to: |
---|
aldehyde dehydrogenase family |
aldehyde dehydrogenase 4 family, member A1; Aldehyde dehydrogenase family 4 member A1; ALDH4DKFZp779M035; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; EC 1.5.1.12; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; P5C dehydrogenase; P5CD; P5CDH
Mass (kDA):
61.719 kDA
Human | |
---|---|
Location: | 1p36.13 |
Sequence: | 1; NC_000001.11 (18871430..18902799, complement) |
Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.
Mitochondrion matrix.
PMID: 8621661 by Hu C.-A., et al. Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase.
PMID: 1395511 by Hempel J., et al. Human liver glutamic gamma-semialdehyde dehydrogenase: structural relationship to the yeast enzyme.