This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
ACBD3 Antibodies
AND ACBD3 ELISA kits, ACBD3 Proteins
Many biological assays use antibodies to detect ACBD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACBD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACBD3 antibodies...
Previous: Septin9
Next: MFSD1
ACBD3 Infographic by Boster Bio
All ACBD3 Products
Product
Figures
Specificity
Applications
Price
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M05645
100 µl
Cat # M05645
100 µl
ACBD3 Overview
Facts about Golgi resident protein GCP60.
Golgi resident protein GCP60 (ACBD3)
Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (PubMed:11590181). Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity).
Recruits PI4KB into the Golgi apparatus membrane; enhances the enzyme action of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the area of the kinase (PubMed:27009356). .
Gene Information
| Human | |
|---|---|
| Gene Name: | ACBD3 |
| Uniprot: | Q9H3P7 |
| Entrez: | 64746 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
acyl-CoA binding domain containing 3; Acyl-CoA-binding domain-containing protein 3; acyl-Coenzyme A binding domain containing 3; GCP60Golgi phosphoprotein 1; GOCAP1Peripheral benzodiazepine receptor-associated protein PAP7; golgi complex associated protein 1, 60kDa; Golgi complex-associated protein 1; Golgi resident protein GCP60; GOLPH1PBR- and PKA-associated protein 7; PAP7; PBR associated protein; peripherial benzodiazepine receptor associated protein; PKA (RIalpha)-associated protein
Molecular Weight
Mass (kDA):
60.593 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q42.12 |
| Sequence: | 1; NC_000001.11 (226144679..226186741, complement) |
Tissue Specificity
Ubiquitous, with highest expression in testis and ovary.
Subcellular Localizations
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Also mitochondrial (via its interaction with PBR).
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Cushing Syndrome
- Picornaviridae Infections
- Endometrial Neoplasms
- Endometrial Polyp
- Enterovirus Infections
- Carcinoma
- Pituitary Diseases
- Deficiency Diseases
- Anemia
- Carney Complex
Interacting Proteins
- PI4KB
- Ppm1l
- TBC1D22A
- TBC1D22B
Pathways
- Localization
- Transport
- Cell Division
- Cholesterol Transport
- Asymmetric Cell Division
- Cell Cycle
- Cell Proliferation
- Regeneration
- Viral Replication
- Cell Adhesion
- Ceramide Transport
- Golgi Localization
- Stem Cell Division
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Golgi Apparatus Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACBD3
bosterbio.com/bosterbio-gene-info-cards/ACBD3
References
PMID: 11590181 by Sohda M., et al. Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin.
PMID: 23572552 by Greninger A.L., et al. ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding.