AASS Antibodies

AND AASS ELISA kits, AASS Proteins

Many biological assays use antibodies to detect AASS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AASS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AASS antibodies...

We validate the specificity of these antibodies to AASS by testing them on tissues known to express AASS positively and negatively. Browse below to find the AASS antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AASS Infographic by Boster Bio

All AASS Products

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Price

Anti-AASS Antibody

7 Q&As

Human

$399
Cat # A07302
100μl

Anti-AASS Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07302-3
100 μg/vial

AASS Overview

Facts about Alpha-aminoadipic semialdehyde synthase, mitochondrial.

AASS 3D structure. Source: alphafold

Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS)

Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal include lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.

Gene Information

Human
Gene Name:	AASS
Uniprot:	Q9UDR5
Entrez:	10157

Family

Belongs to:

No superfamily

Alternative Names

aminoadipate-semialdehyde synthase; aminoadipic semialdehyde synthase; LKR/SDH; LKRSDH; LORSDH; lysine-2-oxoglutarate reductase; mitochondrial

Molecular Weight

Mass (kDA):
102.132 kDA

Genomic Context


Human

Location:	7q31.32
Sequence:	7; NC_000007.14 (122073544..122144269, complement)

Tissue Specificity

Expressed in all 16 tissues examined with highest expression in the liver.

Subcellular Localizations

Mitochondrion.

Diseases

Hyperlysinemias
Tumor Angiogenesis
Heart Diseases
Malignant Neoplasms
Pipecolic Acidemia
Lymphoma
Lung Diseases
Acidemia

Lymphoma, Non-hodgkin
Hodgkin Disease

Pathways

Senescence
Replicative Senescence
Coagulation
Proteolysis
Angiogenesis
Leukocyte Aggregation
Mating

Rna Interference

PTMs

Demethylation
Phosphorylation

Oxidation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AASS

References

PMID: 10775527 by Sacksteder K.A., et al. Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia.

PMID: 463877 by Dancis J., et al. Familial hyperlysinemia: enzyme studies, diagnostic methods, comments on terminology.