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AOC3 Antibodies
AND AOC3 ELISA kits, AOC3 Proteins
Many biological assays use antibodies to detect AOC3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AOC3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AOC3 antibodies...
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AOC3 Infographic by Boster Bio
All AOC3 Products
Product
Figures
Specificity
Applications
Price
Human VAP-1/AOC3 ELISA Kit PicoKine®
2 Citations 10 Q&As
Human
ELISA
$499
Cat # EK1646
96 wells/kit, with removable strips.
Cat # EK1646
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, WB
$380
Cat # A02851-1
100ul
Cat # A02851-1
100ul
Mouse, Rabbit
ELISA, Flow Cytometry, FTA
$349
Cat # M02851
100 &mug
Cat # M02851
100 &mug
AOC3 Overview
Facts about Membrane primary amine oxidase.
Membrane primary amine oxidase (AOC3)
Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity.
May play a role in adipogenesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | AOC3 |
| Uniprot: | Q16853 |
| Entrez: | 8639 |
Family
| Belongs to: |
|---|
| copper/topaquinone oxidase family |
Alternative Names
amine oxidase, copper containing 3 (vascular adhesion protein 1); AOC3; Copper amine oxidase; EC 1.4.3; HPAO; HPAOSSAO; Semicarbazide-sensitive amine oxidase; SSAO; VAP1; VAP-1; VAP1EC 1.4.3.21; VAP-1membrane primary amine oxidase; Vascular adhesion protein 1
Molecular Weight
Mass (kDA):
84.622 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.31 |
| Sequence: | 17; NC_000017.11 (42851182..42858130) |
Tissue Specificity
Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. Isoform 2 seems to be the predominant transcript in fetal kidneys, fetal cartilage and fetal tonsils. The highest relative expression of isoform 2 occurs in skeletal muscle, heart, pancreas, kidney, and lung.
Subcellular Localizations
Cell membrane; Single-pass type II membrane protein.
Diseases
- Tissue Adhesions
- Inflammation
- Extravasation
- Diabetes Mellitus
- Neoplasms
- Obesity
- Liver Diseases
- Atherosclerosis
- Arthritis
- Malignant Neoplasms
- Cardiovascular Diseases
- Vascular Diseases
- Inflammatory Bowel Diseases
Pathways
- Cell Adhesion
- Pathogenesis
- Transport
- Glucose Transport
- Leukocyte Migration
- Glycosylation
- Secretion
- Inflammatory Response
- Lymphocyte Migration
- Localization
- Insulin Secretion
- Blood Circulation
- Glomerular Filtration
PTMs
- Deamination
- Oxidation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AOC3
bosterbio.com/bosterbio-gene-info-cards/AOC3
References
PMID: 8972912 by Zhang X., et al. Cloning and sequencing of a copper-containing, topaquinone-containing monoamine oxidase from human placenta.
PMID: 9653080 by Smith D.J., et al. Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule.
2 Publications of Boster AOC3 Antibodies & ELISA Kits
- PubMed ID: 10.1093/infdis/jiaa349, Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Pat...
- PubMed ID: -, Mingyue Shen,Xianxiang Chen,Lixin Huang,Qiang Yu,Yi Chen,Jianhua Xie,Sulfated Me...
*More publications can be found for each product on its corresponding product page