Actin-related protein 2 Antibodies

AND ACTR2 ELISA kits, Actin-related protein 2 Proteins

Many biological assays use antibodies to detect Actin-related protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Actin-related protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Actin-related protein 2 antibodies...

We validate the specificity of these antibodies to Actin-related protein 2 by testing them on tissues known to express ACTR2 positively and negatively. Browse below to find the ACTR2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACTR2 Infographic by Boster Bio

All ACTR2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A03898
100ul

Anti-Arp2/ACTR2 Antibody Picoband®

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03898-1
100 μg/vial

Anti-Arp2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M03898
100 μl/vial

ACTR2 Overview

Facts about Actin-related protein 2.

ACTR2 3D structure. Source: alphafold

Actin-related protein 2 (ACTR2)

ATP-binding part of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the power for cell motility (PubMed:9000076).

Seems to contact the pointed end of the daughter actin filament (PubMed:9000076). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947).

Gene Information

Human
Gene Name:	ACTR2
Uniprot:	P61160
Entrez:	10097

Family

Belongs to:

actin family

Alternative Names

actin-related protein 2; ARP2 (actin-related protein 2, yeast) homolog; ARP2 actin-related protein 2 homolog (yeast); ARP2Actin-like protein 2

Molecular Weight

Mass (kDA):
44.761 kDA

Genomic Context


Human

Location:	2p14
Sequence:	2; NC_000002.12 (65227695..65271253)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection. Nucleus.

Diseases

Wiskott-aldrich Syndrome
Tissue Adhesions
Protrusion
Shigella Infections
Spinocerebellar Ataxia, Autosomal Recessive 1
Vaccinia
Malignant Neoplasms
Neoplasms
Cell Invasion
Immunologic Deficiency Syndromes
Dysplasia
Infective Disorder
Melanoma

Neoplasm Invasiveness
Carcinoma
Yersinia Infections
Disease Caused By Shigella Flexneri
Adenocarcinoma
Nervousness
Bulla

Pathways

Actin Nucleation
Localization
Cell Motility
Endocytosis
Locomotion
Cell Migration
Transport
Rna Interference
Pathogenesis
Chemotaxis
Phagocytosis
Clathrin-mediated Endocytosis
Receptor-mediated Endocytosis

Arp2/3 Complex-mediated Actin Nucleation
Hemostasis
Vesicle Transport
Actin Filament Network Formation
Actin Filament Polymerization
Cell Death
Cell Growth

PTMs

Phosphorylation
Dephosphorylation
Prenylation

Cleavage
Methylation
Ribosylation

Ubiquitination

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTR2

References

PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

PMID: 9000076 by Welch M.D., et al. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.