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- Table of Contents
Facts about Long-chain-fatty-acid--CoA ligase ACSBG1.
Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate varied saturated, monosaturated and polyunsaturated fatty acids.
Human | |
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Gene Name: | ACSBG1 |
Uniprot: | Q96GR2 |
Entrez: | 23205 |
Belongs to: |
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ATP-dependent AMP-binding enzyme family |
acyl-CoA synthetase bubblegum family member 1EC 6.2.1.3; BG1; BGMBG; bubblegum; FLJ30320; hBG1; hsBG; hsBGM; KIAA0631GR-LACS; lipidosin; long-chain-fatty-acid--CoA ligase ACSBG1; LPD; MGC14352; very long-chain acyl-CoA synthetase
Mass (kDA):
81.29 kDA
Human | |
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Location: | 15q25.1 |
Sequence: | 15; NC_000015.10 (78167468..78234625, complement) |
Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary.
Cytoplasm. Cytoplasmic vesicle. Microsome. Endoplasmic reticulum. Cell membrane.
PMID: 10954726 by Steinberg S.J., et al. Very long-chain acyl-CoA synthetases. Human 'bubblegum' represents a new family of proteins capable of activating very long-chain fatty acids.
PMID: 12975357 by Pei Z., et al. The acyl-CoA synthetase 'bubblegum' (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation.