This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Aldo-keto reductase family 1 member C1.
May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability.
Human | |
---|---|
Gene Name: | AKR1C1 |
Uniprot: | Q04828 |
Entrez: | 1645 |
Belongs to: |
---|
aldo/keto reductase family |
20 alpha-hydroxysteroid dehydrogenase; 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; AKR1C1; Aldo-keto Reductase 1C1; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha(3-alpha)-hydroxysteroid dehydrogenase); AldoketoReductase 1C1; C9; Chlordecone reductase homolog HAKRC; DD1/DD2; DD1MGC8954; DDH1; DDHH-37; dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase isoform DD1; EC 1.1.1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.149,2-ALPHA-HSD; EC 1.3.1.20; HAKRC; HAKRCDDH1aldo-keto red
Mass (kDA):
36.788 kDA
Human | |
---|---|
Location: | 10p15.1 |
Sequence: | 10; NC_000010.11 (4963415..4983283) |
Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
Cytoplasm.
PMID: 8486699 by Stolz A., et al. cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.
PMID: 8132567 by Lou H., et al. Genomic organization and chromosomal localization of a novel human hepatic dihydrodiol dehydrogenase with high affinity bile acid binding.