ANAPC15 Antibodies

AND ANAPC15 ELISA kits, ANAPC15 Proteins

Many biological assays use antibodies to detect ANAPC15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ANAPC15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ANAPC15 antibodies...

We validate the specificity of these antibodies to ANAPC15 by testing them on tissues known to express ANAPC15 positively and negatively. Browse below to find the ANAPC15 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANAPC15 Infographic by Boster Bio

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C11orf51 (ANAPC15) (NM_014042) Human Over-expression Lysate

Human

$628
Cat # LS025906
100 µg

ANAPC15 Overview

Facts about Anaphase-promoting complex subunit 15.

ANAPC15 3D structure. Source: alphafold

Anaphase-promoting complex subunit 15 (ANAPC15)

Component of the anaphase promoting complex/cyclosome (APC/C), a mobile cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. From the complex, plays a role in the release of the mitotic checkpoint complex (MCC) in the APC/C: not required for APC/C action itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint.

Also required for degradation of CDC20. .

Gene Information

Human
Gene Name:	ANAPC15
Uniprot:	P60006
Entrez:	25906

Family

Belongs to:

APC15 family

Alternative Names

anaphase promoting complex subunit 15; APC15; C11orf51; chromosome 11 open reading frame 51; DKFZP564M082; HSPC020; hypothetical protein LOC25906

Molecular Weight

Mass (kDA):
14.281 kDA

Genomic Context


Human

Location:	11q13.4
Sequence:	11; NC_000011.10 (72106372..72112776, complement)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANAPC15

References

PMID: 21926987 by Mansfeld J., et al. APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

PMID: 25043029 by Chang L., et al. Molecular architecture and mechanism of the anaphase-promoting complex.