ARID4B Antibodies

AND ARID4B ELISA kits, ARID4B Proteins

Many biological assays use antibodies to detect ARID4B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARID4B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARID4B antibodies...

We validate the specificity of these antibodies to ARID4B by testing them on tissues known to express ARID4B positively and negatively. Browse below to find the ARID4B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARID4B Infographic by Boster Bio

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BRCAA1 (ARID4B) (NM_031371) Human Over-expression Lysate

Human

$960
Cat # LS051742
100 µg

ARID4B Overview

Facts about AT-rich interactive domain-containing protein 4B.

ARID4B 3D structure. Source: alphafold

AT-rich interactive domain-containing protein 4B (ARID4B)

Acts as a transcriptional repressor. May be the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.

Gene Information

Human
Gene Name:	ARID4B
Uniprot:	Q4LE39
Entrez:	51742

Family

Belongs to:

No superfamily

Alternative Names

180 kDa Sin3-associated polypeptide; ARID domain-containing protein 4B; AT rich interactive domain 4B (RBP1- like); AT rich interactive domain 4B (RBP1-like); AT-rich interactive domain-containing protein 4B; BRCAA1DKFZp313M2420; breast cancer-associated antigen 1; Breast cancer-associated antigen BRCAA1; breast carcinoma-associated antigen; Histone deacetylase complex subunit SAP180; Rb-binding protein homolog; RBBP1L1RBP1L1BCAA; RBP1-like protein; retinoblastoma binding protein 1-like 1; Retinoblastoma-binding protein 1-like 1; SAP180MGC163290; SIN3A-associated protein 180; Sin3-associated p

Molecular Weight

Mass (kDA):
147.809 kDA

Genomic Context


Human

Location:	1q42.3
Sequence:	1; NC_000001.11 (235166895..235328224, complement)

Tissue Specificity

Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasmic in breast cancer cells.

Diseases

Malignant Neoplasms
Mammary Neoplasms
Stomach Neoplasms
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Neoplasms
Early Gastric Cancer
Retinoblastoma
Malignant Neoplasm Of Stomach
Leukemia
Myelomonocytic Leukemia
Metastatic Malignant Neoplasm To The Lung

Pancytopenia
Carcinoma
Leukemia, Myelocytic, Acute
Animal Mammary Neoplasms
Myeloid Leukemia
Pancreatic Neoplasm

Interacting Proteins

ETS1
NHSL2

Pathways

Chromatin Remodeling
Methylation
Cell Cycle
Cell Differentiation
Dna Methylation

PTMs

Methylation

Glycosylation

Research Areas

Cancer
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARID4B

References

PMID: 11481388 by Cao J.-N., et al. RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis.

PMID: 12724404 by Fleischer T.C., et al. Identification and characterization of three new components of the mSin3A corepressor complex.