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- Table of Contents
Facts about Androgen-dependent TFPI-regulating protein.
Human | |
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Gene Name: | ADTRP |
Uniprot: | Q96IZ2 |
Entrez: | 84830 |
Belongs to: |
---|
AIG1 family |
Androgen-dependent TFPI-regulating protein
Mass (kDA):
26.842 kDA
Human | |
---|---|
Location: | 6p24.1 |
Sequence: | 6; NC_000006.12 (11713523..11779628, complement) |
Expressed in cultured endothelial cells and in placenta.
Cell membrane; Multi-pass membrane protein. Colocalized with TFPI and CAV1 in lipid rafts.
PMID: 21868574 by Lupu C., et al. Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen.
PMID: 27018888 by Parsons W.H., et al. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs.