Product Info Summary
SKU: | M01802 |
---|---|
Size: | 100 μl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Acetyl-CoA Carboxylase Monoclonal Antibody
View all Acetyl-CoA Carboxylase alpha/ACACA Antibodies
SKU/Catalog Number
M01802
BM4414 is an alternative SKU for this antibody, used in previous lots.
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-Acetyl-CoA Carboxylase Monoclonal Antibody catalog # M01802. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Acetyl-CoA Carboxylase Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01802)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
EDI-1
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human Acetyl-CoA Carboxylase ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACC Alpha (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACC Beta (ACC2) is the major isoform in skeletal muscle and heart.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01802 is reactive to ACACA in Human, Mouse, Rat
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Observed Molecular Weight
55 kDa
Calculated molecular weight
50976 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01802 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-1:2000
IHC 1:50-1:200
Positive Control
IHC: human kidney tissue
Validation Images & Assay Conditions
Click image to see more details
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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Immunohistochemical analysis of paraffin-embedded human kidney, using Acetyl-CoA Carboxylase Antibody.
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Click image to see more details
Western blot analysis of Acetyl-CoA Carboxylase expression in A431 cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For ACACA (Source: Uniprot.org, NCBI)
Gene Name
ACACA
Full Name
Acetyl-CoA carboxylase 1
Weight
50976 MW
Alternative Names
Heterogeneous nuclear ribonucleoprotein K;hnRNP K;Transformation up-regulated nuclear protein;TUNP;HNRNPK;HNRPK; ACACA ACACD, ACC, ACC1, ACCA, ACACA acetyl-CoA carboxylase alpha acetyl-CoA carboxylase 1|ACC-alpha|acetyl-Coenzyme A carboxylase alpha
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ACACA, check out the ACACA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ACACA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Acetyl-CoA Carboxylase Monoclonal Antibody (M01802)
Hello CJ!
M01802 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Zhang H,Liu S,Cai Z,Dong W,Ye J,Cai Z,Han Z,Liang Y,Zhuo Y,Luo Y,Zhu X,Deng Y,Zhang Y,Liu R,Feng Y, Lai J,Zhou R,Tan H,Zhong W. Down-regulation of ACACA suppresses the malignant progression of Prostate Cancer through inhibiting mitochondrial potential. J
Species: Human
M01802 usage in article: APP:WB, SAMPLE:DU145 CELLS AND PC3 CELLS, DILUTION:NA
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Customer Q&As
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2 Customer Q&As for Anti-Acetyl-CoA Carboxylase Monoclonal Antibody
Question
What sample was tested in WB and IHC applications with M01802?
Verified customer
Asked: 2020-01-09
Answer
Western blot analysis of Acetyl-CoA Carboxylase expression in A431 cell lysate.
Boster Scientific Support
Answered: 2020-01-09
Question
Is this M01802 anti-Acetyl-CoA Carboxylase Monoclonal antibody reactive to the isotypes of ACACA?
Verified Customer
Verified customer
Asked: 2019-09-20
Answer
The immunogen of M01802 anti-Acetyl-CoA Carboxylase Monoclonal antibody is A synthesized peptide derived from human Acetyl-CoA Carboxylase ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACC Alpha (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACC Beta (ACC2) is the major isof. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-09-20