ARHGEF15 Antibodies

AND ARHGEF15 ELISA kits, ARHGEF15 Proteins

Many biological assays use antibodies to detect ARHGEF15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGEF15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGEF15 antibodies...

We validate the specificity of these antibodies to ARHGEF15 by testing them on tissues known to express ARHGEF15 positively and negatively. Browse below to find the ARHGEF15 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGEF15 Infographic by Boster Bio

All ARHGEF15 Products

Product

Figures

Specificity

Applications

Price

Anti-ARHGF ARHGEF15 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A11012
100ul

Rho guanine exchange factor 15 (ARHGEF15) (NM_173728) Human Recombinant Protein

$1249
Cat # PROTO94989
20 µg

Rho guanine exchange factor 15 (ARHGEF15) (NM_173728) Human Over-expression Lysate

Human

$628
Cat # LS022899
100 µg

ARHGEF15 Overview

Facts about Rho guanine nucleotide exchange factor 15.

ARHGEF15 3D structure. Source: alphafold

Rho guanine nucleotide exchange factor 15 (ARHGEF15)

Particular GEF for RhoA activation.
Doesn't activate RAC1 or CDC42.

Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse growth by curbing the synapse-promoting activity of EPHB2.

Gene Information

Human
Gene Name:	ARHGEF15
Uniprot:	O94989
Entrez:	22899

Family

Belongs to:

No superfamily

Alternative Names

ARGEF15Rho GEF 15; E5; Ephexin5; Ephexin-5; FLJ13791; KIAA0915Vsm-RhoGEFephexin-5; MGC44868; Rho guanine exchange factor (GEF) 15; Rho guanine nucleotide exchange factor (GEF) 15; rho guanine nucleotide exchange factor 15

Molecular Weight

Mass (kDA):
91.94 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (8310241..8322516)

Tissue Specificity

Expressed in the vascular smooth muscle of coronary artery.

Subcellular Localizations

Cell projection, dendrite. Expressed exclusively in dendrites of the developing hippocampus.

Diseases

Tumor Angiogenesis
Disorder Of Eye
Malignant Neoplasms
Pathologic Neovascularization
Carcinoma, Lewis Lung

Interacting Proteins

CEP55

Pathways

Angiogenesis
Cell Motility
Tube Formation

PTMs

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGEF15

References

PMID: 12775584 by Ogita H., et al. EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells.

PMID: 23647072 by Veeramah K.R., et al. Exome sequencing reveals new causal mutations in children with epileptic encephalopathies.