Attractin Antibodies

Attractin (ATRN)

Involved in the initial immune cell clustering during inflammatory reaction and might regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair colour.

Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).

Gene Information

Human
Gene Name:	ATRN
Uniprot:	O75882
Entrez:	8455

Family

Belongs to:
No superfamily

Alternative Names

ATRN; Attractin; DPPT-L; KIAA0548; Mahogany Protein; MGC126754; MGCA

Molecular Weight

Mass (kDA):
158.537 kDA

Genomic Context

Human
Location:	20p13
Sequence:	20; NC_000020.11 (3471018..3651118)

Tissue Specificity

Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.

Diseases

• Obesity
• Nerve Degeneration
• Nervousness
• Neurodegenerative Disorders
• Malignant Paraganglionic Neoplasm
• Melanoma
• Neoplasms
• Tissue Adhesions
• Demyelinating Diseases
• Prion Diseases
• Carcinoma
• Malignant Neoplasms

• Cns Disorder
• Diabetes Mellitus
• Diabetes Mellitus, Non-insulin-dependent
• Neuropathology Disease
• Inflammation
• Malignant Squamous Cell Neoplasm
• Skin Neoplasms

Pathways

• Pigmentation
• Myelination
• Energy Homeostasis
• Cell Adhesion
• Transport
• Cell Migration
• Localization
• Paracrine Signaling
• Pathogenesis
• Cell Activation
• Aging
• T Cell Activation
• Immune Response

• Dna Repair
• Interleukin-10 Production
• Chemotaxis
• Cell Death
• Tissue Remodeling
• Oligodendrocyte Development
• Oligodendrocyte Differentiation

PTMs

• Glycosylation

• Phosphorylation

Research Areas

• Cancer
• GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATRN

Best Uses Of The ATRN Marker

Boster Bio offers high-affinity primary antibodies to meet your research needs. Our antibodies are highly cited and trusted by researchers. They are validated for use in ELISA, immunohistochemistry, and Western blotting, and provide you with the best results possible. We will be discussing the ATRN Marker and Boster's products in this article.

Boster has high-affinity prima antibodies

Flow cytometry is the preferred method for many purposes. Flowcytometry is a versatile tool that uses a sample (usually cells or particles) to identify specific proteins. Boster Bio offers high affinity primary antibodies in both monoclonal as well as polyclonal formats. Boster Bio's high-affinity antibodies have been in use for over 25 years and are highly cited.

Boster Bio specializes in developing research antibodies and ELISA kits for detection of biomarkers in cancer, neurosciences, developmental biology, and inflammation. Their high-affinity primary antibodies were tested against 250 untransfected cells and tissues. Their antibodies also have high sensitivity levels, reaching picograms. Boster Bio also sells a wide range immunological reagents such as ELISA kits.

Boster Bio has high-affinity prim antibodies that allow researchers to ask more detailed questions about specimens. High-affinity secondary antibodies can also easily be conjugated to high-affinity primaries. Boster Bio is the ideal choice for research due to its versatility. You can expect outstanding results every time. So, how do you go about choosing the best ones? Here's an overview.