Attractin Antibodies

AND ATRN ELISA kits, Attractin Proteins

Many biological assays use antibodies to detect Attractin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Attractin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Attractin antibodies...

We validate the specificity of these antibodies to Attractin by testing them on tissues known to express ATRN positively and negatively. Browse below to find the ATRN antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATRN Infographic by Boster Bio

All ATRN Products

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Product

Figures

Specificity

Applications

Price

Anti-Attractin ATRN Antibody

Human

ELISA, WB

$380
Cat # A05902
100ul

Attractin (ATRN) (NM_139322) Human Recombinant Protein

$813
Cat # PROTO75882
20 µg

Human Attractin ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2135
96 wells/kit, with removable strips.

Attractin (ATRN) (NM_139322) Human Over-expression Lysate

Human

$628
Cat # LS008455
100 µg

ATRN Overview

Facts about Attractin.

ATRN 3D structure. Source: alphafold

Attractin (ATRN)

Involved in the initial immune cell clustering during inflammatory reaction and might regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair colour.

Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).

Gene Information

Human
Gene Name:	ATRN
Uniprot:	O75882
Entrez:	8455

Family

Belongs to:

No superfamily

Alternative Names

ATRN; Attractin; DPPT-L; KIAA0548; Mahogany Protein; MGC126754; MGCA

Molecular Weight

Mass (kDA):
158.537 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (3471018..3651118)

Tissue Specificity

Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.

Diseases

Obesity
Nerve Degeneration
Nervousness
Neurodegenerative Disorders
Malignant Paraganglionic Neoplasm
Melanoma
Neoplasms
Tissue Adhesions
Demyelinating Diseases
Prion Diseases
Carcinoma
Malignant Neoplasms

Cns Disorder
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Neuropathology Disease
Inflammation
Malignant Squamous Cell Neoplasm
Skin Neoplasms

Pathways

Pigmentation
Myelination
Energy Homeostasis
Cell Adhesion
Transport
Cell Migration
Localization
Paracrine Signaling
Pathogenesis
Cell Activation
Aging
T Cell Activation
Immune Response

Dna Repair
Interleukin-10 Production
Chemotaxis
Cell Death
Tissue Remodeling
Oligodendrocyte Development
Oligodendrocyte Differentiation

PTMs

Glycosylation

Phosphorylation

Research Areas

Cancer
GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATRN

References

PMID: 10811918 by Tang W., et al. Secreted and membrane attractin result from alternative splicing of the human ATRN gene.

PMID: 7539799 by Duke-Cohan J.S., et al. A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26).