ADGRB1 Antibodies

AND ADGRB1 ELISA kits, ADGRB1 Proteins

Many biological assays use antibodies to detect ADGRB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADGRB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADGRB1 antibodies...

We validate the specificity of these antibodies to ADGRB1 by testing them on tissues known to express ADGRB1 positively and negatively. Browse below to find the ADGRB1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADGRB1 Infographic by Boster Bio

All ADGRB1 Products

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Specificity

Applications

Price

Anti-BAI-1 (Q732) ADGRB1 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A32346
100ul

BAI1 (ADGRB1) (NM_001702) Human Over-expression Lysate

Human

$960
Cat # LS000575
100 µg

ADGRB1 Overview

Facts about Adhesion G protein-coupled receptor B1.

ADGRB1 3D structure. Source: alphafold

Adhesion G protein-coupled receptor B1 (ADGRB1)

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells (PubMed:24509909). Also mediates the binding and engulfment of Gram-negative germs (PubMed:26838550).

Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed:26838550). Promotes myoblast fusion (By similarity).

Gene Information

Human
Gene Name:	ADGRB1
Uniprot:	O14514
Entrez:	575

Family

Belongs to:

G-protein coupled receptor 2 family

Alternative Names

BAI1; brain-specific angiogenesis inhibitor 1; FLJ41988; GDAIF

Molecular Weight

Mass (kDA):
173.501 kDA

Genomic Context


Human

Location:	8q24.3
Sequence:	8; NC_000008.11 (142449649..142545009)

Tissue Specificity

Expressed in brain (at protein level) (PubMed:12074842, PubMed:12507886). Expressed on mononuclear phagocytes and monocyte-derived macrophages in the gastric mucosa (at protein level) (PubMed:24509909). Expressed in normal pancreatic tissue but not in pancreatic tumor tissue (PubMed:11875720). Reduced or no expression is observed in some glioblastomas (PubMed:12507886).

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell projection, phagocytic cup. Cell junction, focal adhesion. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density.; [Vasculostatin-120]: Secreted.; [Vasculostatin-40]: Secreted.

Diseases

Tumor Angiogenesis
Neoplasms
Pathologic Neovascularization
Malignant Neoplasms
Brain Neoplasms
Glioblastoma
Glioma
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Neoplasm Metastasis
Carcinoma
Lung Neoplasms

Adenocarcinoma
Ischemia
Cerebral Ischemia
Cell Invasion
Glioblastoma Multiforme
Stomach Neoplasms
Brain Ischemia

Pathways

Angiogenesis
Localization
Cell Adhesion
Phagocytosis
Cell Proliferation
Tube Formation
Cell Cycle
Pathogenesis
Tissue Homeostasis
Apoptotic Cell Clearance
Cell Migration
Brain Development
Proteolysis

Endothelial Cell Proliferation
Cytokinesis
Regulation Of Phagocytosis
Dna Repair
Methylation
Endothelial Cell Migration
Neuroprotection

PTMs

Cleavage
Phosphorylation

Methylation
Demethylation

Research Areas

Alzheimers Research
Angiogenesis
Apoptosis
Cancer
GPCR

Neurodegeneration
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADGRB1

References

PMID: 9393972 by Nishimori H., et al. A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis.

PMID: 9647739 by Shiratsuchi T., et al. Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.